SELECTED:
Functional associations of evolutionarily recent human genes exhibit sensitivity to the 3D genome landscape and disease.
Fleck K*, Luria V*, Garag N, Karger A, Hunter T, Marten D, Phu W, Nam KM, Sestan N, O’Donnell-Luria AH, Erceg J. bioRxiv (2024).
The 3D genome landscape: Diverse chromosomal interactions and their functional implications.
Fleck K*, Raj R*, Erceg J. Front Cell Dev Biol 10:968145 (2022).
The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos.
Erceg J*, AlHaj Abed J*, Goloborodko A*, Lajoie BR, Fudenberg G, Abdennur N, Imakaev M, McCole RB, Nguyen SC, Saylor W, Joyce EF, Senaratne TN, Hannan MA, Nir G, Dekker J, Mirny LA, Wu CT. Nat Commun 10, 4486 (2019).
Highly structured homolog pairing reflects functional organization of the Drosophila genome.
AlHaj Abed J*, Erceg J*, Goloborodko A*, Nguyen SC, McCole RB, Saylor W, Fudenberg G, Lajoie BR, Dekker J, Mirny LA, Wu CT. Nat Commun 10, 4485 (2019).
Ultraconserved elements occupy specific arenas of three-dimensional mammalian genome organization.
McCole RB*, Erceg J*, Saylor W, Wu CT. Cell Reports 24: 479-488 (2018).
Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements.
Erceg J*, Pakozdi T*, Marco-Ferreres R*, Ghavi-Helm Y, Girardot C, Bracken AP, Furlong EE. Genes Dev 31: 590-602 (2017).
Subtle Changes in Motif Positioning Cause Tissue-Specific Effects on Robustness of an Enhancer's Activity.
Erceg J, Saunders TE, Girardot C, Devos DP, Hufnagel L, Furlong EE. PLoS Genet 10: e1004060 (2014)
OTHER:
Islands of retroelements are major components of Drosophila centromeres.
Chang CH*, Chavan A*, Palladino J*, Wei X, Martins NMC, Santinello B, Chen CC, Erceg J, Beliveau BJ, Wu CT, Larracuente AM, Mellone BG. PLoS Biology 17, e3000241 (2019).
Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling.
Nir G*, Farabella I*, Pérez Estrada C*, Ebeling CG*, Beliveau BJ, Sasaki HM, Lee SH, Nguyen SC, McCole RB, Chattoraj S, Erceg J, AlHaj Abed J, Martins NMC, Nguyen HQ, Hannan MA, Russell S, Durand NC, Rao SSP, Kishi JY, Soler-Vila P, Di Pierro M, Onuchic JN, Callahan S, Schreiner J, Stuckey J, Yin P, Lieberman Aiden E, Marti-Renom MA, Wu CT. PLoS Genet 14, e1007872 (2018).
Structural disruption of genomic regions containing ultraconserved elements is associated with neurodevelopmental phenotypes.
McCole RB, Saylor W, Redin C, Fonseka CY, Brand H, Erceg J, Talkowski ME, Wu CT. bioRxiv: https://doi.org/10.1101/233197 (2017).
Pairing and anti-pairing: a balancing act in the diploid genome.
Joyce EF, Erceg J, Wu CT. Curr Opin Genet Dev 37: 119-128 (2016).
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes.
Beliveau BJ, Boettiger AN, Avendaño MS, Jungmann R, McCole RB, Joyce EF, Kim-Kiselak C, Bantignies F, Fonseka CY, Erceg J, Hannan MA, Hoang HG, Colognori D, Lee JT, Shih WM, Yin P, Zhuang X, Wu CT. Nat Commun 6:7147 (2015).
Enhancer detection in zebrafish permits the identification of neuronal subtypes that express Hox4 paralogs.
Punnamoottil B, Kikuta H, Pezeron G, Erceg J, Becker TS, Rinkwitz S. Dev Dyn 237: 2195-2208 (2008).
*equal contribution